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Invitrogen™ eIF4E2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5110849
Description
Immunogen sequence: TERDKNQSSS KRKAVVPGPA EHPLQYNYTF WYSRRTPGRP TSSQSYEQNI KQIGTFASVE QFWRFYSHMV RPGDLTGHSD FHLFKEGIKP MWEDDANKNG GKWIIRL.
Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation (PubMed:9582349, PubMed:17368478, PubMed:25624349). Acts as a repressor of translation initiation (PubMed:22751931). In contrast to EIF4E, it is unable to bind eIF4G (EIF4G1, EIF4G2 or EIF4G3), suggesting that it acts by competing with EIF4E and block assembly of eIF4F at the cap. [UniProt].
Specifications
eIF4E2 | |
Polyclonal | |
Unconjugated | |
EIF4E2 | |
2700069E09Rik; 4EHP; 4E-LP; AI036339; AV129531; D0H0S6743E; EGK_04904; eIF4E type 2; eIF-4E type 2; Eif4e2; eIF4E-2; EIF4EL3; eIF4E-like cap-binding protein; eIF4E-like protein 4E-LP; eukar; eukaryotic translation initiation factor 4E family member 2; eukaryotic translation initiation factor 4E homologous protein; eukaryotic translation initiation factor 4E like 3; eukaryotic translation initiation factor 4E member 2; eukaryotic translation initiation factor 4E type 2; Eukaryotic translation initiation factor 4E-like 3; h4EHP; IF4e; mRNA cap-binding protein 4EHP; mRNA cap-binding protein type 2; mRNA cap-binding protein type 3 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
9470 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunocytochemistry | |
0.05 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
O60573 | |
EIF4E2 | |
Recombinant Protein corresonding to Human eIF4E2. Recombinant protein control fragment (Product #RP-89635). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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