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Invitrogen™ eIF4E2 Polyclonal Antibody
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Catalog No. PIPA5116997
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100 μL
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PIPA5116997 100 μL
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Catalog No. PIPA5116997 Supplier Invitrogen™ Supplier No. PA5116997
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Description

Rabbit Polyclonal Antibody

Positive Samples: BT-474, HL-60, Mouse kidney Immunogen sequence: MNNKFDALKD DDSGDHDQNE ENSTQKDGEK EKTERDKNQS SSKRKAVVPG PAEHPLQYNY TFWYSRRTPG RPTSSQSYEQ NIKQIGTFAS VEQFWRFYSH MVRPGDLTGH SDFHLFKEGI KPMWEDDANK NGGKWIIRLR KGLASRCWEN LILAMLGEQF MVGEEICGAV VSVRFQEDII SIWNKTASDQ ATTARIRDTL RRVLNLPPNT IMEYKTHTDS IKMPGRLGPQ RLLFQNLWKP.

Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation (PubMed:9582349, PubMed:17368478, PubMed:25624349). Acts as a repressor of translation initiation (PubMed:22751931). In contrast to EIF4E, it is unable to bind eIF4G (EIF4G1, EIF4G2 or EIF4G3), suggesting that it acts by competing with EIF4E and block assembly of eIF4F at the cap. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen eIF4E2
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.26 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.3
Gene EIF4E2
Gene Accession No. O60573, Q8BMB3
Gene Alias 2700069E09Rik; 4EHP; 4E-LP; AI036339; AV129531; D0H0S6743E; EGK_04904; eIF4E type 2; eIF-4E type 2; Eif4e2; eIF4E-2; EIF4EL3; eIF4E-like cap-binding protein; eIF4E-like protein 4E-LP; eukar; eukaryotic translation initiation factor 4E family member 2; eukaryotic translation initiation factor 4E homologous protein; eukaryotic translation initiation factor 4E like 3; eukaryotic translation initiation factor 4E member 2; eukaryotic translation initiation factor 4E type 2; Eukaryotic translation initiation factor 4E-like 3; h4EHP; IF4e; mRNA cap-binding protein 4EHP; mRNA cap-binding protein type 2; mRNA cap-binding protein type 3
Gene Symbols EIF4E2
Host Species Rabbit
Immunogen Recombinant Protein (or fragment).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26987, 363275, 9470
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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