Invitrogen™ eIF4G3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA555208

Catalog No. PIPA555208

Description

Immunogen sequence: EFDSRRTLTS RGSMGREKND KPLPSATARP NTFMRGGSSK DLLDNQSQEE QRREMLETVK QLTGGVDVER NSTEAERNKT RESAKPEISA MSA Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 78%.

The protein encoded by this gene is thought to be part of the eIF4F protein complex, which is involved in mRNA cap recognition and transport of mRNAs to the ribosome. Interestingly, a microRNA (miR-520c-3p) has been found that negatively regulates synthesis of the encoded protein, and this leads to a global decrease in protein translation and cell proliferation. Therefore, this protein is a key component of the anti-tumor activity of miR-520c-3p.

Specifications

• Antigen: eIF4G3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EIF4G3
• Gene Alias: 1500002J22Rik; 4833436O05; 4930523M17Rik; eIF4G 3; eIF-4G 3; Eif4g3; eIF-4-gamma 3; eIF-4-gamma II; eIF4GII; eukaryotic translation initiation factor 4 gamma 3; eukaryotic translation initiation factor 4 gamma, 3; G1-419-52; repro8; RP11-190H11.1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8672
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O43432
• Gene Symbols: EIF4G3
• Immunogen: Recombinant protein corresponding to Human eIF4G3. Recombinant protein control fragment (Product #RP-94018).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG