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Invitrogen™ eIF5A Polyclonal Antibody
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Catalog No. PIPA596035
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100 μL
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PIPA596035 100 μL
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Catalog No. PIPA596035 Supplier Invitrogen™ Supplier No. PA596035
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MADDLDFETG DAGASATFPM QCSALRKNGF VVLKGRPCKI VEMSTSKTGK HGHAKVHLVG IDIFTGKKYE DICPSTHNMD VPNIKRNDFQ LIGIQDGYLS LLQDSGEVRE DLRLPEGDLG KEIEQKYDCG EEILITVLSA MTEEAAVAIK AMAK; Positive Samples: HeLa, 293T, Raji, 22Rv1, HepG2, K-562, U-251MG, Mouse liver, Mouse testis; Cellular Location: Cytoplasm, Cytoplasmic side, Endoplasmic reticulum membrane, Nucleus, Peripheral membrane protein, nuclear pore complex.

mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of TP53/p53 and TP53/p53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.
TRUSTED_SUSTAINABILITY

Specifications

Antigen eIF5A
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.18 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene EIF5A
Gene Accession No. P63241, P63242
Gene Alias AA410058; D19Wsu54e; Eif4d; eIF-4D; Eif5a; eIF-5A; EIF5A1; eIF-5A1; eIF-5A-1; eIF5AI; eukaryotic initiation factor 5A; Eukaryotic initiation factor 5A isoform 1; eukaryotic translation initiation factor 5A; eukaryotic translation initiation factor 5A-1; MGC104255; MGC99547; OTTHUMP00000128384; Rev-binding factor; uORF A
Gene Symbols EIF5A
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-154 of human eIF5A (NP_0011372341).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1984, 276770
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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