Invitrogen™ eIF5A2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120894

Catalog No. PIPA5120894

Description

Positive test controls include: U-87MG, SKOV3, SW480, THP-1, Mouse lung, Mouse brain, Mouse spleen, Rat lung. The target is usually found in the following locations: Cytoplasm, Cytoplasmic side, Endoplasmic reticulum membrane, Nucleus, Peripheral membrane protein, nuclear pore complex. Immunogen sequence: MADEIDFTTG DAGASSTYPM QCSALRKNGF VVLKGRPCKI VEMSTSKTGK HGHAKVHLVG IDIFTGKKYE DICPSTHNMD VPNIKRNDYQ LICIQDGYLS LLTETGEVRE DLKLPEGELG KEIEGKYNAG EDVQVSVMCA MSEEYAVAIK PCK.

mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation.

Specifications

• Antigen: eIF5A2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EIF5A2
• Gene Alias: 9630038B20; EIF5A2; eIF-5A2; eIF-5A-2; eIF5AII; eukaryotic initiation factor 5A; Eukaryotic initiation factor 5A isoform 2; eukaryotic translation initiation factor 5A2; Eukaryotic translation initiation factor 5A-2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 208691, 310261, 56648
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.66 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q8BGY2, Q9GZV4
• Gene Symbols: EIF5A2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-153 of human EIF5A2 (NP_065123.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG