Invitrogen™ eIF5B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA536456

Catalog No. PIPA536456

Description

This antibody detects endogenous protein at a molecular weight of 139 kDa. Purity is >95% by SDS-PAGE.

Accurate initiation of translation in eukaryotes is complex and requires many factors, some of which are composed of multiple subunits. The process is simpler in prokaryotes which have only three initiation factors (IF1, IF2, IF3). Two of these factors are conserved in eukaryotes: the homolog of IF1 is eIF1A and the homolog of IF2 is eIF5B. This gene encodes eIF5B. Factors eIF1A and eIF5B interact on the ribosome along with other initiation factors and GTP to position the initiation methionine tRNA on the start codon of the mRNA so that translation initiates accurately.

Specifications

• Antigen: eIF5B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EIF5B
• Gene Alias: A030003E17Rik; Annexin V-binding protein ABP-7; BC018347; DKFZp434I036; eIF 5B; Eif5b; eIF-5B; Eukaryotic translation initiation factor 5B; FLJ10524; If2; KIAA0741; translation initiation factor IF2; Translation initiation factor IF-2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 226982, 308306, 9669
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: B2GUV7, O60841, Q05D44
• Gene Symbols: EIF5B
• Immunogen: Synthetic peptide corresponding to amino acids 1061-1110 of human eIF5B.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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