Invitrogen™ ELA3A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA528155

Catalog No. PIPA528155

Description

Recommended positive controls: PC-3. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3A has little elastolytic activity. Like most of the human elastases, elastase 3A is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3A preferentially cleaves proteins after alanine residues. Elastase 3A may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1.

Specifications

• Antigen: ELA3A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CELA3A
• Gene Alias: CELA3A; chymotrypsin like elastase family member 3A; chymotrypsin-like elastase family member 3A; chymotrypsin-like elastase family, member 3A; ELA3; ELA3A; elastase 1; elastase 3A, pancreatic; elastase IIIA; Elastase-3A; Gm13011; OTTMUSG00000009877; protease E; uncharacterized protein LOC242711
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10136
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P09093
• Gene Symbols: CELA3A
• Immunogen: Recombinant protein encompassing a sequence within the center region of human Elastase 3A. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG