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Invitrogen™ ELAC2 Polyclonal Antibody
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Catalog No. PIPA554016
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100 μL
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PIPA554016 100 μL
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Catalog No. PIPA554016 Supplier Invitrogen™ Supplier No. PA554016
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: WMERFGPDTQ HLVLNENCAS VHNLRSHKIQ TQLNLIHPDI FPLLTSFRCK KEGPTLSVPM VQGECLLKYQ LRPRREWQRD AIITCNPEEF IVEALQLPNF QQSVQEYR Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 79%.

ELAC2 encodes a protein that has a C-terminal domain with tRNA 3 processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ELAC2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Elac2
Gene Accession No. Q9BQ52
Gene Alias 1110017O07Rik; COXPD17; D11Wsu80e; elaC homolog 2; elaC homolog 2 (E. coli); elaC homolog protein 2; elaC ribonuclease Z 2; ELAC2; elaC-like protein 2; ELC2; heredity prostate cancer protein 2; HPC2; putative prostate cancer susceptibility protein HPC2/ELAC2; ribonuclease Z 2; RNase Z 2; tRNA 3 endonuclease 2; tRNase Z (long form); tRNase Z 2; tRNase Z(L); zinc phosphodiesterase ELAC protein 2
Gene Symbols Elac2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ELAC2. Recombinant protein control fragment (Product #RP-92519).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 60528
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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