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Invitrogen™ ELAC2 Polyclonal Antibody
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Catalog No. PIPA5106313
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100 μL
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PIPA5106313 100 μL
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Catalog No. PIPA5106313 Supplier Invitrogen™ Supplier No. PA5106313
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total ELAC2.

ELAC2 encodes a protein that has a C-terminal domain with tRNA 3 processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ELAC2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Elac2
Gene Accession No. Q80Y81, Q8CGS5, Q9BQ52
Gene Alias 1110017O07Rik; COXPD17; D11Wsu80e; elaC homolog 2; elaC homolog 2 (E. coli); elaC homolog protein 2; elaC ribonuclease Z 2; ELAC2; elaC-like protein 2; ELC2; heredity prostate cancer protein 2; HPC2; putative prostate cancer susceptibility protein HPC2/ELAC2; ribonuclease Z 2; RNase Z 2; tRNA 3 endonuclease 2; tRNase Z (long form); tRNase Z 2; tRNase Z(L); zinc phosphodiesterase ELAC protein 2
Gene Symbols Elac2
Host Species Rabbit
Immunogen A synthesized peptide derived from human ELAC2(Accession Q9BQ52), corresponding to amino acid residues H114-A164.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 282826, 60528, 68626
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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