ELAC2 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A304774A

Catalog No. 50-156-8639

Description

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections. Based on 100% sequence identity, this antibody is predicted to react with Gorilla and Chimpanzee

The protein encoded by this gene has a C-terminal domain with tRNA 3 processing endoribonuclease activity, which catalyzes the removal of the 3′ trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].

Specifications

• Antigen: ELAC2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ELAC2
• Gene Alias: ELC2, HPC2, RNase Z 2, elaC homolog protein 2, heredity prostate cancer protein 2, putative prostate cancer susceptibility protein HPC2/ELAC2, ribonuclease Z 2, tRNA 3 endonuclease 2, tRNase Z (long form), tRNase Z 2, zinc phosphodiesterase ELAC protein 2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 60528
• Content And Storage: 4° C
• Form: Liquid

• Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
• Concentration: 1 mg/ml
• Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
• Gene Accession No.: Q9BQ52
• Gene Symbols: ELAC2
• Immunogen: Between 150 and 200
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG