Elastin Antibody (ELN/1981) - Azide and BSA Free, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP275770

Catalog No. NBP275770

Description

Elastin Monoclonal specifically detects Elastin in Human samples. It is validated for ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array.

Specifications

• Antigen: Elastin alpha
• Classification: Monoclonal
• Concentration: 0.2 mg/ml
• Dilution: ELISA, Immunohistochemistry-Paraffin 1-2 ug/ml
• Gene Accession No.: P15502
• Gene Symbols: ELN
• Immunogen: Recombinant full-length human Elastin protein (Uniprot: P15502)
• Purification Method: Protein A or G purified
• Research Discipline: Extracellular Matrix
• Gene ID (Entrez): 2006.0
• Target Species: Human
• Form: Purified

• Applications: ELISA, Immunohistochemistry (Paraffin)
• Clone: ELN/1981
• Conjugate: Unconjugated
• Formulation: 10 mM PBS with No Preservative
• Gene Alias: elastin, FLJ38671, FLJ43523, SVAS, tropoelastin, WBS, WS
• Host Species: Mouse
• Molecular Weight of Antigen: 70 kDa
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries. It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticity to the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension.
• Content And Storage: Store at 4°C.
• Isotype: IgG1 κ