Invitrogen™ Elastin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596196

Catalog No. PIPA596196

Description

Immunogen sequence: GGVPGAIPGG VPGGVFYPGA GLGALGGGAL GPGGKPLKPV PGGLAGAGLG AGLGAFPAVT FPGALVPGGV ADAAAAYKAA KAGAGLGGVP GVGGLGVSAG AVVPQPGAGV KPGKVPGVGL PGVYPGGVLP GARFPGVGVL PGVPTGAGVK PKAPGVGGAF AGIPGVGPFG GPQP; Positive Samples: A375, 293T, HL-60, Mouse heart, Rat heart; Cellular Location: extracellular matrix, extracellular space.

This gene encodes a protein that is one of the two components of elastic fibers. The encoded protein is rich in hydrophobic amino acids such as glycine and proline, which form mobile hydrophobic regions bounded by crosslinks between lysine residues. Deletions and mutations in this gene are associated with supravalvular aortic stenosis (SVAS) and autosomal dominant cutis laxa. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: Elastin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ELN
• Gene Alias: 5830419M17Rik; AI385707; AI480567; AW229038; BB105748; E030024M20Rik; elastin; elastin (supravalvular aortic stenosis, Williams-Beuren syndrome); elastin a precursor; elastin b precursor; elastin c precursor; elastin microfibril interface located protein 1; elastin microfibril interface-located protein 1; Elastin microfibril interfacer 1; Eln; EMI; EMILIN; EMILIN1; EMILIN-1; FLJ38671; FLJ43523; gp115; RATTREL11; SVAS; TREL11; Trela; Trela26; Tropoelastin; WBS; WS
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13717, 2006, 25043
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.39 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: P15502, P54320, Q99372
• Gene Symbols: ELN
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 27-200 of human ELN (NP_0012658681).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG