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Invitrogen™ ELL Monoclonal Antibody (OTI3A8)
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Catalog No. PIMA527364
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Quantity:
100 μL
Catalog No. Quantity
PIMA527364 100 μL
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Catalog No. PIMA527364

Supplier: Invitrogen™ MA527364

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Description

Mouse Monoclonal Antibody

ELL Monoclonal Antibody for Western Blot, IHC (P)

Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Elongation factor component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968, PubMed:23932780). Specifically required for stimulating the elongation step of RNA polymerase II- and III-dependent snRNA gene transcription (PubMed:23932780). ELL also plays an early role before its assembly into in the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site. Required to stabilize the pre-initiation complex and early elongation. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen ELL
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI3A8
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Ell
Gene Accession No. O08856, P55199
Gene Alias C19orf17; Eleven-nineteen lysine-rich leukemia protein; Ell; ELL gene (11-19 lysine-rich leukemia gene); ELL1; elongation factor for RNA polymerase II; elongation factor RNA polymerase II; hypothetical protein LOC325221; MEN; PPP1R68; protein phosphatase 1, regulatory subunit 68; RNA polymerase II elongation factor ELL; RNA POLYMERASE II ELONGATION FACTOR ELL (ELEVEN-NINETEEN LYSINE-RICH LEUKEMIA PROTEIN); wu:fc60b11; zgc:63836
Gene Symbols Ell
Host Species Mouse
Immunogen Human recombinant protein fragment corresponding to amino acids 302-621 of ELL produced in E.coli.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13716, 8178
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b
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