Invitrogen™ ELOVL6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5106662

Catalog No. PIPA5106662

Description

Antibody detects endogenous levels of total ELOVL6.

Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 6 (ELOVL6) is a member of fatty acyl-CoA elongase gene family that converts palmitic to stearic acid and it has been shown to be a target of SREBP-1, playing an important role in de novo synthesis of long-chain saturated and monosaturated fatty acids in conjunction with fatty acid synthase and stearoyl-CoA desaturase ELOVL6 was predicted to be important for tissue fatty acid composition. Recent studies suggest that inhibition of this elongase could be a new therapeutic approach for ameliorating insulin resistance, diabetes and cardiovascular risks, even in the presence of a continuing state of obesity.

Specifications

• Antigen: ELOVL6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ELOVL6
• Gene Alias: 3-keto acyl-CoA synthase Elovl6; C77826; Elongation of very long chain fatty acids protein 6; ELOVL FA elongase 6; ELOVL family member 6, elongation of long chain fatty acids; ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast); ELOVL family member 6, elongation of long chain fatty acids (yeast); ELOVL fatty acid elongase 6; ELOVL6; FACE; FAE; fatty acid elongase 2; Fatty acyl-CoA elongase; hELO2; Lce; Lce2; long chain fatty acid elongase; long chain fatty acyl elongase; long-chain fatty-acyl elongase; Masr; Myelin-associated SUR4 protein; rELO2; Very long chain 3-ketoacyl-CoA synthase 6; very long chain 3-oxoacyl-CoA synthase 6; very-long-chain 3-oxoacyl-CoA synthase 6
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 170439, 171402, 79071
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q920L5, Q920L6, Q9H5J4
• Gene Symbols: ELOVL6
• Immunogen: A synthesized peptide derived from human ELOVL6(Accession Q9H5J4), corresponding to amino acid residues N29-L79.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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