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ELOVL6 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501987695
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50-198-7695 100 μL
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Catalog No. 50-198-7695 Supplier Bioss Supplier No. BS7055R
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Rabbit Polyclonal Antibody

Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 6 (ELOVL6) is a member of fatty acyl-CoA elongase gene family that converts palmitic to stearic acid and it has been shown to be a target of SREBP-1, playing an important role in de novo synthesis of long-chain saturated and monosaturated fatty acids in conjunction with fatty acid synthase and stearoyl-CoA desaturase ELOVL6 was predicted to be important for tissue fatty acid composition. Recent studies suggest that inhibition of this elongase could be a new therapeutic approach for ameliorating insulin resistance, diabetes and cardiovascular risks, even in the presence of a continuing state of obesity.

Specifications

Antigen ELOVL6
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene ELOVL6
Gene Accession No. Q9H5J4
Gene Alias 3-keto acyl-CoA synthase ELOVL6; C77826; Elongation of very long chain fatty acids protein 6; ELOVL FA elongase 6; ELOVL family member 6, elongation of long chain fatty acids; ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast); ELOVL family member 6, elongation of long chain fatty acids (yeast); ELOVL fatty acid elongase 6; ELOVL6; Face; FAE; Fatty acid elongase 2; Fatty acyl-CoA elongase; hELO2; LCE; Lce2; Long chain fatty acid elongase; long chain fatty acyl elongase; Long-chain fatty-acyl elongase; Masr; Myelin-associated SUR4 protein; rELO2; Very long chain 3-ketoacyl-CoA synthase 6; Very long chain 3-oxoacyl-CoA synthase 6; very-long-chain 3-oxoacyl-CoA synthase 6
Gene Symbols ELOVL6
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human ELOVL6.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79071
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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