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Tocris Bioscience™ EM 12-FS
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Catalog No. 785150
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Catalog No. Quantity
78-515-0 50 mg
78-511-0 10 mg
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Catalog No. 78-515-0 Supplier Tocris Bioscience™ Supplier No. 7851/50
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Description

Molecular glue; induces degradation of NQAT1

EM12-FS is a selective N-terminal glutamine amidohydrolase 1 (NTAQ1) Degrader. In MOLT4 cells, it downregulates NTAQ1 via cereblon-mediated degradation (IC50 = 256 nM). Requires covalent His353 engagement to recruit and degrade NTAQ1.

Specifications

Chemical Name or Material 3-[6-[(Fluorosulfonyl)oxy]-1,3-dihydro-1-oxo-2H-isoindol-2-yl]-2,6-piperidinedione
CAS 2839138-44-0
Quantity 50 mg
Target Molecular Glues
Molecular Formula C13H11FN2O6S
Purity 0.95
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