Invitrogen™ Embigin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531921

Catalog No. PIPA531921

Description

Recommended positive controls: 293T, A431, Jurkat, Raji. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Embigin is a 327 amino acid regulatory protein belonging to the immunoglobulin superfamily class of CAMs, and has two Ig-like (immunoglobulin-like) V- type domains. In situ hybridization analysis shows that Embigin has specific carbohydrate epitopes and plays an important role in early postimplantation embryogenesis. A highly glycosylated transmembrane glycoprotein, Embigin acts as a regulator of cell/ECM interactions during development and homeostasis of normal adult tissues. Transfection studies suggest its role in promotion of integrin-mediated cell-substratum adhesion. Widely expressed in most of the tissues and embryonal carcinoma cells, prostate and mammary cancer cell lines, it may also help in the classification of human carcinomas.

Specifications

• Antigen: Embigin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EMB
• Gene Alias: AL022799; EMB; Embigin; embigin homolog; glycoprotein 70; Gp70; Teratocarcinoma glycoprotein Gp-70
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 133418
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.75 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q6PCB8
• Gene Symbols: EMB
• Immunogen: Recombinant protein encompassing a sequence within the center region of human EMB. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG