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Tocris Bioscience™ EMD 527040 hydrochloride
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Catalog No. 75085
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75-085 5 mg
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Catalog No. 75-085 Supplier Tocris Bioscience™ Supplier No. 7508/5
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Description

ανβ6 integrin inhibitor

EMD 527040 hydrochloride is an inhibitor of integrin αVβ6. EMD 527040 inhibits binding of αVβ6 to fibronectin and attachment of cells expressing αVβ6 to fibronectin (IC50 values = 6 nM and 1.6 μM, respectively). EMD 527040 shows antifibrotic effects in an animal model of biliary fibrosis and is active in vivo.

Specifications

Chemical Name or Material N-[1-Oxo-5-(2-pyridinylamino)pentyl]-O-(phenylmethyl)-L-seryl-3-(3,5-dichlorophenyl)-β-alanine hydrochloride
Quantity 5 mg
Target Integrin Receptor Inhibitors
Molecular Formula C29H32Cl2N4O5.HCl
Purity 0.98
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