MilliporeSigma™ Superoxide Dismutase, Human, Recombinant Protein, E. coli

Description

Recombinant, human superoxide dismutase expressed in E. coli as a homodimer consisting of 2 identical, 154-amino acid chains. Purified by proprietary chromatographic methods. Superoxide dismutase is an essential component of biological defense against the toxic effects of oxygen. It catalyzes the dismutation of superoxide radicals to molecular oxygen and H₂O₂ and plays a role in cellular aging due to its reduced activity in aging cells. Mutant forms of Cu/Zn SOD are associated with neurodegenerative disease.

Specifications

• Formulation: Lyophilized from 100mM NaCl, 50mM sodium phosphate buffer.
• Preparation Method: Reconstitute in sterile MQ water to a final concentration of ≥100μg/mL. Further dilute in aqueous buffers just prior to use.
• Purification Method: SDS-PAGE
• Quantity: 100 μg
• Source: E. coli
• Immunogen: Superoxide Dismutase
• Storage Requirements: Following reconstitution, refrigerate (4°C) for short-term storage or aliquot and freeze (−20°C) for long-term storage. Stock solutions are stable for up to 2 weeks at 4°C or for up to 4 months at −20°C.
• Regulatory Status: RUO
• Species: Human
• Recombinant: Recombinant
• Form: Solid
• Purity or Quality Grade: ≥90%