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Tocris Bioscience™ EMPA
GSA_VA

Catalog No. 455850
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Catalog No. Quantity
45-585-0 50 mg
45-581-0 10 mg
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Catalog No. 45-585-0 Supplier Tocris Bioscience™ Supplier No. 4558/50
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Description

Highly potent and selective OX2 antagonist; brain penetrant

Highly potent, selective OX2 receptor antagonist (IC50 values are 2.3 nM and 1900 nM for OX2 and OX1 respectively). Displays negligible or no inhibition of a panel of 80 receptors. Blocks orexin-B- and orexin-A-invoked calcium mobilization in hOX2-expressing CHO cells (IC50 values are 7.9 nM and 8.8 nM respectively); reverses orexin-B-induced hyperlocomotion in mice. Brain penetrant.

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Chemical Identifiers

CAS 680590-49-2
Molecular Formula C23H26N4O4S

Specifications

Quantity 50 mg
Formula Weight 454.54
Purity >98%
Molecular Weight (g/mol) 454.545
Chemical Name or Material EMPA

Safety and Handling

Recommended Storage Store at -20°C
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