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EMR1 Polyclonal Antibody, Invitrogen™

Catalog No. PIPA521399
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PIPA521399 100 μL
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Catalog No. PIPA521399 Supplier Thermo Scientific Supplier No. PA521399

Description

Rabbit Polyclonal Antibody

Recommended positive controls: Jurkat, Raji, K562, C8D30, NIH-3T3, Raw264.7, C2C12, rat liver. Predicted reactivity: Mouse (86%), Rat (84%), Dog (84%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

EMR1 has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. EMR1 is the human ortholog of murine F4/80 but unlike F4/80, the expression of EMR1 in humans is restricted to eosinophils and is not expressed on macrophage populations.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EMR1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.23 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene ADGRE1
Gene Accession No. Q14246, Q5Y4N8, Q61549
Gene Alias ADGRE1; Adhesion G protein-coupled receptor E1; Adhesion G protein-coupled receptor E2; cell surface glycoprotein EMR1; cell surface glycoprotein F4/80; DD7A5-7; egf-like module containing, mucin-like, hormone receptor-like 1; EGF-like module containing, mucin-like, hormone receptor-like sequence 1; EGF-like module receptor 1; EGF-like module-containing mucin-like hormone receptor-like 1; EGF-TM7; Emr1; EMR1 hormone receptor; F4/80; Gpf480; Ly71; lymphocyte antigen 71; TM7LN3
Gene Symbols ADGRE1
Host Species Rabbit
Immunogen Recombinant fragment corresponding to a region within amino acids 626 and 886 of EMR1 (Uniprot ID#Q14246)
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13733, 2015, 316137
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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