EMR3 Antibody (3D7), Alexa Fluor™ 350, Novus Biologicals™

Armenian Hamster Monoclonal Antibody

Supplier:  Novus Biologicals NB10065935AF350

Catalog No. N10693A30

Description

EMR3 Monoclonal specifically detects EMR3 in Human samples. It is validated for Flow Cytometry.

Specifications

• Antigen: EMR3
• Classification: Monoclonal
• Conjugate: Alexa Fluor 350
• Formulation: 50 mM sodium borate with 0.05% sodium azide
• Gene Symbols: ADGRE3
• Immunogen: ARHO-EMR3-CD97 (EGF1) transfectants.
• Primary or Secondary: Primary
• Test Specificity: NB100-65935 recognizes human epidermal growth factor (EGF) module-containing mucin-like hormone receptor 3 (EMR3), which is a 56kD member of the EGF-7 transmembrane (TM7) family of adhesion receptors. EMR3 is expressed at the cell surface as a heterodimer. The molecule is predominantly expressed on granulocytes, and at lower levels on mature myeloid cells, monocytes and dendritic cells. EMR3 is absent on lymphocytes, haematopoietic stem cells and myeloid progenitors. Studies suggest that the EMR3 molecule is up-regulated during late stages of neutrophil differentiation and is a marker for terminally differentiated cells. The exact functions of EMR3 and its ligands have not yet been determined.
• Content And Storage: Store at 4°C in the dark.

• Applications: Flow Cytometry
• Clone: 3D7
• Dilution: Flow Cytometry
• Gene Alias: egf-like module containing, mucin-like, hormone receptor-like 3, EGF-like module receptor 3, EGF-like module-containing mucin-like hormone receptor-like 3, egf-like module-containing mucin-like receptor 3
• Host Species: Armenian Hamster
• Quantity: 0.1 mL
• Gene ID (Entrez): 84658
• Target Species: Human
• Isotype: IgG