Invitrogen™ EMX2 Monoclonal Antibody (4D8)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA518821

Catalog No. PIMA518821

Description

Peptide Sequence: HSPHPLFASQ QRDPSTFYPW LIHRYRYLGH RFQGNDTSPE SFLLHNALAR KPKRIRTAFS PSQLLRLEHA FEKNHYVVGA ERKQLAHSLS LTETQVKV.

This gene encodes a homeobox-containing transcription factor that is the homolog to the 'empty spiracles' gene in Drosophila. Research on this gene in humans has focused on its expression in three tissues: dorsal telencephalon, olfactory neuroepithelium, and urogenetial system. It is expressed in the dorsal telencephalon during development in a low rostral-lateral to high caudal-medial gradient and is proposed to pattern the neocortex into defined functional areas. It is also expressed in embryonic and adult olfactory neuroepithelia where it complexes with eukaryotic translation initiation factor 4E (eIF4E) and possibly regulates mRNA transport or translation. In the developing urogenital system, it is expressed in epithelial tissues and is negatively regulated by HOXA10. Alternative splicing results in multiple transcript variants encoding distinct proteins.

Specifications

• Antigen: EMX2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: Q04743
• Gene Symbols: EMX2
• Immunogen: EMX2 (NP_004089, 103 a.a. ~ 200 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b κ

• Applications: ELISA, Immunocytochemistry
• Clone: 4D8
• Conjugate: Unconjugated
• Gene: EMX2
• Gene Alias: empty spiracles homeobox 2; empty spiracles homolog 2; Empty spiracles-like protein 2; Emx2; Emx-2; Homeobox protein EMX2; Pdo; RGD1564797
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2018
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid