Invitrogen™ ENC-2 Monoclonal Antibody (1B7)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA515656

Catalog No. PIMA515656

Description

MA5-15656 targets KLHL25 in indirect ELISA, WB applications and shows reactivity with Human samples. The MA5-15656 immunogen is purified recombinant fragment of human KLHL25 expressed in E. Coli. . MA5-15656 detects KLHL25 which has a predicted molecular weight of approximately 65kDa.

KLHL25 (ectoderm-neural cortex protein 2, ENC2) is a cytoplasmic protein that contains six Kelch regions and a single BTB (POZ) domain. KLHL25 is highly homologus to another Kelch-like protein, ENC1, and it is believed to operate in a manner similar to other Kelch-domain containing proteins. Kelch-domain repeat containing proteins often act as modifiers of Actin fibers. Expressed early in embryogenesis, ENC1 helps to mediate neuronal process formation. It also appears to have a role in neural crest cell differentiation. KLHL25 likely functions as a substrate specific adapter for protein ubiquitinating complexes. KLHL25 is expressed in most tissues with highest expression in brain and liver.

Specifications

• Antigen: ENC-2
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: ascites with 0.03% sodium azide
• Gene Accession No.: Q9H0H3
• Gene Symbols: KLHL25
• Immunogen: Purified recombinant fragment of human KLHL25 expressed in E. Coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 64410
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Western Blot
• Clone: 1B7
• Conjugate: Unconjugated
• Gene: KLHL25
• Gene Alias: 2810402K13Rik; BC027373; BTB/POZ KELCH domain protein; ectodermal-neural cortex 2; ectoderm-neural cortex protein 2; ectoderm-neural cortex-1; Enc-1; ENC2; ENC-2; FLJ12587; FLJ45015; kelch like family member 25; kelch-like 25; kelch-like family member 25; kelch-like protein 25; KLHL25; RGD1310815
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b