Invitrogen™ ENC-2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531115

Catalog No. PIPA531115

Description

Recommended positive controls: NT2D1. Predicted reactivity: Mouse (96%), Rat (95%), Xenopus laevis (92%), Rhesus Monkey (99%), Bovine (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

KLHL25 (ectoderm-neural cortex protein 2, ENC2) is a cytoplasmic protein that contains six Kelch regions and a single BTB (POZ) domain. KLHL25 is highly homologus to another Kelch-like protein, ENC1, and it is believed to operate in a manner similar to other Kelch-domain containing proteins. Kelch-domain repeat containing proteins often act as modifiers of Actin fibers. Expressed early in embryogenesis, ENC1 helps to mediate neuronal process formation. It also appears to have a role in neural crest cell differentiation. KLHL25 likely functions as a substrate specific adapter for protein ubiquitinating complexes. KLHL25 is expressed in most tissues with highest expression in brain and liver.

Specifications

• Antigen: ENC-2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KLHL25
• Gene Alias: 2810402K13Rik; BC027373; BTB/POZ KELCH domain protein; ectodermal-neural cortex 2; ectoderm-neural cortex protein 2; ectoderm-neural cortex-1; Enc-1; ENC2; ENC-2; FLJ12587; FLJ45015; kelch like family member 25; kelch-like 25; kelch-like family member 25; kelch-like protein 25; KLHL25; RGD1310815
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 207952, 293023, 64410
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.69 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q4KLM4, Q8R2P1, Q9H0H3
• Gene Symbols: KLHL25
• Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human KLHL25. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov