Endoglin/CD105 Antibody (MJ7/18), Janelia Fluor™ 646, Novus Biologicals™

Rabbit Monoclonal Antibody

Supplier:  Novus Biologicals NBP281085JF646

Catalog No. NB015711

Description

Endoglin/CD105 Monoclonal specifically detects Endoglin/CD105 in Mouse samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence.

Specifications

• Antigen: Endoglin/CD105
• Classification: Monoclonal
• Conjugate: Janelia Fluor 646
• Formulation: 50mM Sodium Borate
• Gene Symbols: ENG
• Immunogen: MJ7/18 was prepared by immunizing rats with inflamed mouse skin tissue. The antibody was selected immunohistologically for reactivity with endothelial cells.
• Quantity: 0.1 mL
• Research Discipline: Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Extracellular Matrix, Hypoxia, Immunology, Mesenchymal Stem Cell Markers, Stem Cell Markers
• Gene ID (Entrez): 2022
• Target Species: Mouse
• Form: Purified

• Applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence
• Clone: MJ7/18
• Dilution: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence
• Gene Alias: CD105, CD105 antigen, endoglin, ENDOsler-Rendu-Weber syndrome 1, HHT1FLJ41744, ORW, ORW1
• Host Species: Rabbit
• Purification Method: Protein A purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: MJ7/18 binds specifically to mouse Endoglin/CD105. Endoglin/CD105 is a homodimer expressed by vascular endothelial cells. Endoglin/CD105 functions in adhesion and embryonic angiogenesis. Endoglin/CD105 is a major homodimeric glycoprotein of vascular endothelium involved in cell ahesion through integrin/RGD binding and the regulation of angiogenesis. Also acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Endoglin/CD105 is also required for GDF2/BMP9 signaling through SMAD1 in endothelial cells.
• Content And Storage: Store at 4°C in the dark.
• Isotype: IgG κ