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Endoglin/CD105 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
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Catalog No. 501726665 Shop All Proteintech Group Inc Products
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50-172-6665 150 μL
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Catalog No. 50-172-6665 Supplier Proteintech Group Inc Supplier No. 108621AP150UL
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Description

Rabbit Polyclonal Antibody

CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.

Specifications

Antigen Endoglin/CD105
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene ENG
Gene Accession No. P17813, Q63961
Gene Alias CD105, END, Endoglin, ENG, HHT1, ORW, ORW1
Gene Symbols Eng
Host Species Rabbit
Immunogen Endoglin/CD105 Fusion Protein Ag1287
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13805, 2022, 497010
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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