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Endoglin/CD105 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501735816 Shop All Proteintech Group Inc Products
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50-173-5816 150 μL
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Catalog No. 50-173-5816 Supplier Proteintech Group Inc Supplier No. 281171AP150UL
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Rabbit Polyclonal Antibody

Endoglin (Osler-Rendu-Weber syndrome 1), CD105, is a type I membrane glycoprotein located on cell surfaces and is a part of the TGF beta receptor complex. Its gene is mapped to human chromosome 8. The protein consists of a homodimer of 180 kDA with disulfide links. It has been found on endothelial cells, activated macrophages, fibroblasts and smooth muscle cells. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling and has been found to be elevated in pregt women who subsequently develop preeclampsia.

Specifications

Antigen Endoglin/CD105
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene ENG
Gene Accession No. P17813
Gene Alias CD105, END, Endoglin, ENG, FLJ41744, HHT1, ORW, ORW1
Gene Symbols ENG
Host Species Rabbit
Immunogen Endoglin/CD105 Fusion Protein Ag27822
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2022
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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