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Invitrogen™ Endothelin 3 Polyclonal Antibody
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Catalog No. PIPA576667
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100 μL
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PIPA576667 100 μL
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Catalog No. PIPA576667 Supplier Invitrogen™ Supplier No. PA576667
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Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Endothelin 3
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene EDN3
Gene Accession No. P14138
Gene Alias 114CH19; EDN3; endothelin 3; endothelin-3; ET 3; Et3; ET-3; HSCR4; lethal spotting; ls; MGC15067; MGC61498; PPET3; Preproendothelin 3; preproendothelin-3; preproET-3; RGD1564825; RP4-614C15.1; tmgc48; WS4B
Gene Symbols EDN3
Host Species Rabbit
Immunogen Recombinant full length Human Endothelin 3.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1908
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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