Endothelin A Receptor Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA530589

Catalog No. PIPA530589

Description

Recommended positive controls: U87-MG, GL261. Predicted reactivity: Rhesus Monkey (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: Endothelin A Receptor
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EDNRA
• Gene Alias: Ednra; Endor; Endothelin A; endothelin A receptor; endothelin receptor subtype A; endothelin receptor type A; endothelin type A receptor; endothelin-1 receptor; endothelin-1-specific receptor; ETa; ET-A; ETAR; ET-AR; ETA-R; ETRA; G protein coupled receptor; G protein-coupled receptor; Gpcr10; G-protein coupled receptor 10; hET-AR; MFDA; RGD1559432
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13617, 1909, 24326, 373908
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.78 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: P25101, P26684, Q61614
• Gene Symbols: EDNRA
• Immunogen: Synthetic peptide corresponding to a region within amino acids 363 and 427 of Human Endothelin A Receptor
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Chicken, Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov