Endothelin A Receptor Recombinant Rabbit Monoclonal Antibody (15H24L16), Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen 704014

Catalog No. 70-401-4

Description

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. Recombinant antibodies are produced using specific genes that code for the desired antibodies. These genes are cloned into an expression vector and expressed in vitro. The advantages of recombinant antibodies include better specificity and lot-to-lot consistency. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: Endothelin A Receptor
• Classification: Recombinant Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P25101
• Gene Symbols: EDNRA
• Immunogen: Peptide corresponding to residues aa 408-427 of human EDNRA
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

• Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
• Clone: 15H24L16
• Conjugate: Unconjugated
• Gene: EDNRA
• Gene Alias: Ednra; Endor; Endothelin A; endothelin A receptor; endothelin receptor subtype A; endothelin receptor type A; endothelin type A receptor; endothelin-1 receptor; endothelin-1-specific receptor; ETa; ET-A; ETAR; ET-AR; ETA-R; ETRA; G protein coupled receptor; G protein-coupled receptor; Gpcr10; G-protein coupled receptor 10; hET-AR; MFDA; RGD1559432
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 1909
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Isotype: IgG