Invitrogen™ ENOSF1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531476

Catalog No. PIPA531476

Description

Recommended positive controls: A549, HeLa, HepG2, HCT116. Predicted reactivity: Pig (88%), Bovine (89%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.

Specifications

• Antigen: ENOSF1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ENOSF1
• Gene Alias: antisense RNA to thymidylate synthase; enolase superfamily member 1; ENOSF1; HSRTSBETA; L-fuconate dehydratase; mitochondrial enolase superfamily member 1; rTS; rTS alpha; rTS beta; TYMSAS
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55556
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q7L5Y1
• Gene Symbols: ENOSF1
• Immunogen: Recombinant fragment corresponding to a region within amino acids 13 and 349 of Human ENOSF1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov