Invitrogen™ ENPP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA551105

Catalog No. PA551105

Description

ENPP2 Polyclonal Antibody detects endogenous levels of ENPP2 protein.

The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified.

Specifications

• Antigen: ENPP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ENPP2
• Gene Alias: ATX; ATX-X; autotaxin; AutotaxinATX; autotaxin-t; ectonucleotide pyrophosphatase/phosphodiesterase 2; ectonucleotide pyrophosphatase/phosphodiesterase family member 2; E-NPP 2; Enpp2; Extracellular lysophospholipase D; FLJ26803; lysoPLD; NPP2; Npps2; PD-IALPHA; PDNP2; phosphodiesterase I/nucleotide pyrophosphatase 2; phosphodiesterase I/nucleotide pyrophosphatase 2 (autotaxin); plasma lysophospholipase D
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18606, 5168, 84050
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q13822, Q64610, Q9R1E6
• Gene Symbols: ENPP2
• Immunogen: Synthesized peptide derived from the Internal region of human Autotaxin (aa 401-450).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG