Invitrogen™ ENPP4 Polyclonal Antibody

Catalog No.	Quantity
PIPA553454	100 μL

Catalog No. PIPA553454 Supplier Invitrogen™ Supplier No. PA553454

Description

Rabbit Polyclonal Antibody

Immunogen sequence: DEGWTIVLNE SSQKLGDHGY DNSLPSMHPF LAAHGPAFHK GYKHSTINIV DIYPMMCHIL GLKPHPNNGT FGHTKCLLVD QW Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 88%.

NPP4, also known as ENPP4 (ectonucleotide pyrophosphatase/phosphodiesterase family member 4), is a 453 amino acid single-pass type I membrane protein that belongs to the nucleotide pyrophosphatase/phosphodiesterase family. The gene that encodes NPP4 consists of approximately 16, 736 bases and maps to human chromosome 6p21.1. Making up nearly 6% of the human genome, chromosome 6 contains around 1, 200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene, and Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatibility complex proteins are also located on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6.

Specifications

• Antigen: ENPP4
• Applications: Immunohistochemistry (Paraffin)
• Classification: Polyclonal
• Concentration: 0.05 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: ENPP4
• Gene Accession No.: Q9Y6X5
• Gene Alias: 4933413N07Rik; AA986363; AI195364; AP3A hydrolase; AP3Aase; Bis(5'-adenosyl)-triphosphatase enpp4; ectonucleotide pyrophosphatase/phosphodiesterase 4; ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative function); ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative); ectonucleotide pyrophosphatase/phosphodiesterase family member 4; E-NPP 4; ENPP4; E-NPP4; Gm90; KIAA0879; mKIAA0879; NPP4; NPP-4
• Gene Symbols: ENPP4
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to Human ENPP4. Recombinant protein control fragment (Product #RP-90624).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 22875
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG