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Invitrogen™ ENSA Polyclonal Antibody
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Catalog No. PIPA5105254
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100 μL
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PIPA5105254 100 μL
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Catalog No. PIPA5105254 Supplier Invitrogen™ Supplier No. PA5105254
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total ENSA.

The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ENSA
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ENSA
Gene Accession No. O43768, P60840, P60841
Gene Alias 1700020C18Rik; 2610007F17Rik; AI451924; Alpha-endosulfine; ARPP-19e; endosulfine alpha; endosulfine-alpha variant 1; endosulfine-alpha variant 3; ENSA
Gene Symbols ENSA
Host Species Rabbit
Immunogen A synthesized peptide derived from human ENSA(Accession O43768), corresponding to amino acid residues Y41-L91.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2029, 56205, 60334
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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