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  8. EO 1428, Tocris Bioscience™ 

EO 1428, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
10mg
50mg
This item is not returnable. View return policy
321351-00-2
C20H16BrClN2O
415.715
HDCLCHNAEZNGNV-UHFFFAOYSA-N
unii-mv2rhj680o,mv2rhj680o,p38 map kinase inhibitor viii,4-2-amino-4-bromophenyl amino-2-chlorophenyl 2-methylphenyl methanone,2-methylphenyl-4-2-amino-4-bromophenyl amino-2-chlorophenyl methanone,4-2-amino-4-bromophenyl amino-2-chlorophenyl 2-methylphenyl methanone,methanone, 4-2-amino-4-bromophenyl amino-2-chlorophenyl 2-methylphenyl,4-2-amino-4-bromophenylamino-2-chlorophenyl o-tolyl methanone,4-2-amino-4-bromophenyl amino-2-chlorophenyl o-tolyl methanone,4-2-amino-4-bromo-phenylamino-2-chloro-phenyl-o-tolyl-methanone
9801969
[4-(2-amino-4-bromoanilino)-2-chlorophenyl]-(2-methylphenyl)methanone
CC1=CC=CC=C1C(=O)C2=C(C=C(C=C2)NC3=C(C=C(C=C3)Br)N)Cl
This item is not returnable. View return policy
321351-00-2
C20H16BrClN2O
415.715
HDCLCHNAEZNGNV-UHFFFAOYSA-N
unii-mv2rhj680o,mv2rhj680o,p38 map kinase inhibitor viii,4-2-amino-4-bromophenyl amino-2-chlorophenyl 2-methylphenyl methanone,2-methylphenyl-4-2-amino-4-bromophenyl amino-2-chlorophenyl methanone,4-2-amino-4-bromophenyl amino-2-chlorophenyl 2-methylphenyl methanone,methanone, 4-2-amino-4-bromophenyl amino-2-chlorophenyl 2-methylphenyl,4-2-amino-4-bromophenylamino-2-chlorophenyl o-tolyl methanone,4-2-amino-4-bromophenyl amino-2-chlorophenyl o-tolyl methanone,4-2-amino-4-bromo-phenylamino-2-chloro-phenyl-o-tolyl-methanone
9801969
[4-(2-amino-4-bromoanilino)-2-chlorophenyl]-(2-methylphenyl)methanone
CC1=CC=CC=C1C(=O)C2=C(C=C(C=C2)NC3=C(C=C(C=C3)Br)N)Cl

Description

Selective inhibitor of p38α and p38β2

Selective inhibitor of p38α and p38β 2 that displays no activity at p38γ, p38δ, ERK1/2 and JNK1. Inhibits production of inflammatory cytokines including IL-8, TNF-α, IL-6, IL-1β and IL-10 (IC 50 values are 4, 5, 17, 30 and 74 nM respectively). Displays anti-inflammatory activity in murine models of acute and chronic dermatitis.

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Quantity 10mg
Formula Weight 415.71
Percent Purity >98%
Chemical Name or Material EO 1428

Safety and Handling

Recommended Storage : Store at +4°C