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Tocris Bioscience™ EO 1428
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Catalog No. 290850
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Catalog No. Quantity
29-085-0 50 mg
29-081-0 10 mg
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Catalog No. 29-085-0 Supplier Tocris Bioscience™ Supplier No. 2908/50
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Selective inhibitor of p38α and p38β2

Selective inhibitor of p38α and p38β2 that displays no activity at p38γ, p38δ, ERK1/2 and JNK1. Inhibits production of inflammatory cytokines including IL-8, TNF-α, IL-6, IL-1β and IL-10 (IC50 values are 4, 5, 17, 30 and 74 nM respectively). Displays anti-inflammatory activity in murine models of acute and chronic dermatitis.

Chemical Identifiers

CAS 321351-00-2
Molecular Formula C20H16BrClN2O

Specifications

Quantity 50 mg
Formula Weight 415.71
Purity >98%
Molecular Weight (g/mol) 415.715
Chemical Name or Material EO 1428
Recommended Storage Store at +4°C
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