Invitrogen™ Eotaxin 2 Monoclonal Antibody (61016.11)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA124653

Catalog No. MA124653

Description

The Neutralization Dose50 (ND50) for this antibody is approximately 1 to 5 μg/mL in the presence of 100 ng/mL of recombinant human eotaxin 2, measuring the chemotaxis of rat myeloid Y3 cells transfected with the human CCR3 gene. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Eotaxin 2 belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line.

Specifications

• Antigen: Eotaxin 2
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: O00175
• Gene Symbols: CCL24
• Immunogen: Purified, recombinant human eotaxin 2, expressed in E. coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Inhibition Assays, Neutralization, Western Blot
• Clone: 61016.11
• Conjugate: Unconjugated
• Gene: CCL24
• Gene Alias: CC chemokine CCL24; C-C motif chemokine 24; C-C motif chemokine ligand 24; Ccl24; chemokine (C-C motif) ligand 24; Ckb-6; CK-beta-6; Eosinophil chemotactic protein 2; Eotaxin2; eotaxin-2; eotaxin-2-like protein; MPIF2; MPIF-2; Myeloid progenitor inhibitory factor 2; Scya24; small inducible cytokine A24; small inducible cytokine subfamily A (Cys-Cys), member 24; small-inducible cytokine A24
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 6369
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid