Invitrogen™ Eotaxin 3 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA547851

Catalog No. PIPA547851

Description

In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) Eotaxin, recombinant mouse (rm) Eotaxin, rhEotaxin-2, and rmEotaxin-2 is observed. Reconstitute at 0.2 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

Eotaxin-3 is a small cytokine belonging to the CC chemokine family that is also called CCL26, Chemokine (C-C motif) ligand 26. Chemokines play pivotal roles in health and disease by controlling migration and tissue localization of specific types of cells expressing their cognate receptors. Eotaxin-3 is chemotactic for eosinophils and basophils and elicits its effects by binding to the cell surface chemokine receptor CCR3. It is expressed by several tissues including heart, lung and ovary, and in endothelial cells that have been stimulated with the cytokine interleukin 4. This gene for chemokine is located on human chromosome 7. Eotaxin-3 induced migration of eosinophils and basophils only at a 10-fold higher concentration than eotaxin.

Specifications

• Antigen: Eotaxin 3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CCL26
• Gene Alias: CC chemokine IMAC; C-C motif chemokine 26; C-C motif chemokine ligand 26; Ccl26; Ccl26l; chemokine (C-C motif) ligand 26; chemokine N1; Eotaxin3; eotaxin-3; IMAC; Macrophage inflammatory protein 4-alpha; MGC126714; MIP-4a; MIP-4alpha; MIP-4-alpha; PRO242; SCYA26; SCYA26MIP-4-alpha; small inducible cytokine A26; small inducible cytokine subfamily A (Cys-Cys), member 26; small-inducible cytokine A26; Thymic stroma chemokine-1; TSC-1; UNQ216; UNQ216/PRO242
• Host Species: Goat
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10344
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry, Immunohistochemistry (Paraffin), Neutralization, Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q9Y258
• Gene Symbols: CCL26
• Immunogen: E. coli-derived recombinant human CCL26/Eotaxin-3 Thr24-Leu94.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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