Invitrogen™ Eotaxin Monoclonal Antibody (42285)

Rat Monoclonal Antibody

Supplier:  Invitrogen™ MA523830

Catalog No. PIMA523830

Description

In direct ELISAs and Western blots, less than 10% cross-reactivity with recombinant human (rh) CCL11/Eotaxin, recombinant mouse CCL7, and rhCCL21 is observed. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil specific chemokine assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.

Specifications

• Antigen: Eotaxin
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P48298
• Gene Symbols: CCL11
• Immunogen: E. coli-derived recombinant mouse CCL11/Eotaxin His24-Pro97.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunohistochemistry (Frozen), Neutralization, Western Blot
• Clone: 42285
• Conjugate: Unconjugated
• Gene: CCL11
• Gene Alias: C-C motif chemokine 11; C-C motif chemokine ligand 11; Ccl11; chemokine (C-C motif) ligand 11; eosinophil chemotactic protein; Eotaxin; Eotaxin 1; Eotaxin1; eotaxin-1; MGC22554; Scya11; small chemokine (C-C motif) ligand 11; small inducible cytokine A11; small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin); small inducible cytokine subfamily A11; small-inducible cytokine A11
• Host Species: Rat
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 20292
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized