Invitrogen™ Eotaxin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA519868

Catalog No. PIPA519868

Description

In Western blot applications, a monomer and homodimer are detected at ~9 and ~18kDa. A suggested positive control is Hela cell lysate. PA5-19868 can be used with blocking peptide PEP-0006.

This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil specific chemokine assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.

Specifications

• Antigen: Eotaxin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CCL11
• Gene Alias: C-C motif chemokine 11; C-C motif chemokine ligand 11; Ccl11; chemokine (C-C motif) ligand 11; eosinophil chemotactic protein; Eotaxin; Eotaxin 1; Eotaxin1; eotaxin-1; MGC22554; Scya11; small chemokine (C-C motif) ligand 11; small inducible cytokine A11; small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin); small inducible cytokine subfamily A11; small-inducible cytokine A11
• Host Species: Rabbit
• Purification Method: Ion-exchange chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6356
• Content And Storage: Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: P51671
• Gene Symbols: CCL11
• Immunogen: A peptide corresponding to amino acids near the carboxy terminus of human eotaxin.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG