Invitrogen™ EPB41 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA542239

Catalog No. PIPA542239

Description

Peptide sequence: SESRGLSRLF SSFLKRPKSQ VSEEEGKEVE SDKEKGEGGQ KEIEFGTSLD Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%.

Elliptocytosis is a hematologic disorder characterized by elliptically shaped erythrocytes and a variable degree of hemolytic anemia. Inherited as an autosomal dominant, elliptocytosis results from mutation in any one of several genes encoding proteins of the red cell membrane skeleton. The form discussed here is the one found in the 1950s to be linked to Rh blood group and more recently shown to be caused by a defect in protein 4. 1. 'Rh-unlinked' forms of elliptocytosis are caused by mutation in the alpha-spectrin gene, the beta-spectrin gene, or the band 3 gene.

Specifications

• Antigen: EPB41
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EPB41
• Gene Alias: 4.1R; AI415518; Band 4.1; D4Ertd442e; E41P; EL1; elliptocytosis 1, RH-linked; Elp1; Elp-1; EPB4.1; EPB41; erythrocyte membrane protein band 4.1; erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked); erythrocyte protein band 4.1; erythrocyte skeletal protein; erythrocyte surface protein band 4.1; HE; Kiaa4056; mKIAA4056; P4.1; protein 4.1; Protein 4.1R; RGD1564762
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2035
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: P11171
• Gene Symbols: EPB41
• Immunogen: Synthetic peptide directed towards the N-terminal of human EPB41 (aa 74-123).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG