Invitrogen™ EPB41L2 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA518821

Catalog No. PIPA518821

Description

This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

The 4.1 gene family encodes a group of multifunctional cytoskeletal proteins (4.1R, 4.1G, 4.1N and 4.1B), which are predominantly expressed in the nervous system. 4.1G is a protein that stabilizes spectrin-actin interactions and is associated with hereditary elliptocytosis. Red blood cell 4.1, designated 4.1R, is a multifunctional protein that is essential for maintaining erythrocyte shape and membrane mechanical properties. Both 4.1R and 4.1G are distributed in a unique pattern in the cerebellum and are believed to modulate the membrane mechanical properties of neuronal cells by promoting fodrin/actin association. 4.1N and 4.1B, designated EPB41L1 and EPB41L3, respectively, are strongly expressed in the brain. Antibodies to 4.1N have been reported to detect multiple forms, each enriched in postsynaptic density preparations relative to brain homogenate. Antibodies to 4.1B have been reported to detect two forms.

Specifications

• Antigen: EPB41L2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EPB41L2
• Gene Alias: 4.1G; 4.1-G; AW555191; band 4.1-like protein 2; D10Ertd398e; DKFZp781D1972; DKFZp781H1755; Epb4.1l2; Epb41l2; erythrocyte membrane protein band 4.1 like 2; erythrocyte membrane protein band 4.1 like-protein 2; erythrocyte membrane protein band 4.1-like 2; erythrocyte membrane protein band 4.1-like 2 retinal; erythrocyte protein band 4.1 like 2; erythrocyte protein band 4.1l2 long; erythrocyte protein band 4.1l2 middle; erythrocyte protein band 4.1-like 2; generally expressed protein 4.1; NBL2; OTTHUMP00000040262; RGD1563977; RP3-324N14.1
• Host Species: Goat
• Purification Method: Ammonium Sulfate Precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 2037
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O43491
• Gene Symbols: EPB41L2
• Immunogen: Synthetic peptide sequence (RREVRSPTKAPH) corresponding to the internal amino acids of EPB41L2 (aa 593-605).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG