Invitrogen™ EPC1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5145011

Catalog No. FEPA5145011

Description

Immunogen sequence: SALLQPSNIT QTSSSHSALS HQVTAANSAT TQVLIGNNIR LTVPSSVATV NSIAPINARH IPRTLSAVPS SALKLAAAAN CQ Antigen sequence identity: Mouse 89%; Rat 94%.

EPC1 is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.

Specifications

• Antigen: EPC1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EPC1
• Gene Alias: 2400007E14Rik; 5730566F07Rik; A930032N02Rik; DKFZp781P2312; enhancer of polycomb 1; enhancer of polycomb homolog 1; enhancer of polycomb homolog 1 (Drosophila); Epc1; Epl 1; Epl1; mir-1893
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 80314
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid
• Isotype: IgG

• Applications: Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9H2F5
• Gene Symbols: EPC1
• Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 717-798. Recombinant protein control fragment (Product #RP-109888).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Format: Liquid