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Invitrogen™ EPC1 Polyclonal Antibody
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Catalog No. PIPA576826
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100 μL
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Catalog No. Quantity
PIPA576826 100 μL
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Catalog No. PIPA576826 Supplier Invitrogen™ Supplier No. PA576826
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Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

EPC1 is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EPC1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene EPC1
Gene Accession No. Q8C9X6, Q9H2F5
Gene Alias 2400007E14Rik; 5730566F07Rik; A930032N02Rik; DKFZp781P2312; enhancer of polycomb 1; enhancer of polycomb homolog 1; enhancer of polycomb homolog 1 (Drosophila); Epc1; Epl 1; Epl1; mir-1893
Gene Symbols EPC1
Host Species Rabbit
Immunogen Recombinant full length Human EPC1.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13831, 80314
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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