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Invitrogen™ EPC1 Polyclonal Antibody
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Catalog No. PIPA5140053
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100 μL
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PIPA5140053 100 μL
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Catalog No. PIPA5140053 Supplier Invitrogen™ Supplier No. PA5140053
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Description

Rabbit Polyclonal Antibody

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: DYDSVFHHLD LEMLSSPQHS PVNQFANTSE TNTSDKSFSK DLSQILVNIK SCRWRHFRPR TPSLHDSDND ELSCRKLYRS INRTGTAQPG TQTCSTSTQS KSSSGSAHFA FTAEQYQQHQ QQLALMQKQQ LAQIQQQQA Highest antigen sequence indentity to the following orthologs: Mouse - 83%, Rat - 83%.

EPC1 is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EPC1
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene EPC1
Gene Accession No. Q9H2F5
Gene Alias 2400007E14Rik; 5730566F07Rik; A930032N02Rik; DKFZp781P2312; enhancer of polycomb 1; enhancer of polycomb homolog 1; enhancer of polycomb homolog 1 (Drosophila); Epc1; Epl 1; Epl1; mir-1893
Gene Symbols EPC1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human EPC1. Recombinant protein control fragment (Product #RP-108787).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 80314
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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