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EPC1 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501564282
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50-156-4282 20 μL
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Catalog No. 50-156-4282 Supplier Bethyl Laboratories, Inc Supplier No. A303110AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse

EPC1 is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.

Specifications

Antigen EPC1
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene EPC1
Gene Accession No. Q9H2F5
Gene Alias Enhancer of polycomb homolog 1 (Drosophila), DKFZp781P2312, Epl1
Gene Symbols EPC1
Host Species Rabbit
Immunogen Between 325 and 375
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 80314
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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