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EpCAM/TROP1 Antibody (MOC-31), Novus Biologicals™
SDP

Catalog No. p-5545299 Shop All R&D Systems Products
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NBP24464000 0.02 mg
NBP24464001 0.1 mg
NBP24464002 0.2 mg
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Catalog No. NBP24464000 Supplier Novus Biologicals Supplier No. NBP2446400.02MG
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Description

Mouse Monoclonal Antibody has been used in 3 publications

Ensure accurate, reproducible results in Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

EpCAM/TROP1 Monoclonal specifically detects EpCAM/TROP1 in Human, Rat (Negative) samples. It is validated for Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

Antigen EpCAM/TROP1
Applications Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence
Classification Monoclonal
Clone MOC-31
Concentration 0.2mg/mL
Conjugate Unconjugated
Dilution Western Blot 1:100 - 1:200, Flow Cytometry 5 - 10 ul/million cells in 0.1ml, Immunohistochemistry-Paraffin 1:100 - 1:200, SDS-Page, Immunofluorescence 1:50 - 1:100
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Accession No. P16422
Gene Alias 17-1A, 323/A3, ACSTD1, antigen identified by monoclonal AUA1, CD326 antigen, Cell surface glycoprotein Trop-1, chromosome 4, surface marker (35kD glycoprotein), DIAR5, EGP, EGP-2, EGP314, EGP40, EpCAM, epithelial cell adhesion molecule, Epithelial cell surface antigen, Epithelial glycoprotein, Epithelial glycoprotein 314, ESA, GA733-2EGP34, hEGP314, HNPCC8, KS 1/4 antigen, KS1/4, KSAHEA125, M1S2, M4S1Ly74, Major gastrointestinal tumor-associated protein GA733-2, MIC18MH99, MOC31, TACST-1, TACSTD1, TROP1CD326, Tumor-associated calcium signal transducer 1CO-17A
Gene Symbols EPCAM
Host Species Mouse
Immunogen Neuraminidase treated GLS-1 human small cell lung carcinoma cells
Molecular Weight of Antigen 41 kDa
Purification Method Protein A or G purified
Quantity 0.02 mg
Regulatory Status RUO
Research Discipline Cancer, Cancer Stem Cells
Primary or Secondary Primary
Gene ID (Entrez) 4072
Test Specificity Binding epitope of this antibody is located in the first EGF-like repeat domain (EGF1) between amino acids 27-59 of Ep-CAM. EGP40 is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas with the exception of adult squamous epithelium, hepatocytes and gastric epithelial cells. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.
Target Species Human, Rat (Negative)
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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For Research Use Only

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