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Invitrogen™ EPCR Monoclonal Antibody (LMR-42)
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Catalog No. 01671418
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Catalog No. Quantity
01-671-418 1 mL
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Catalog No. 01-671-418 Supplier Invitrogen™ Supplier No. MA135363
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Description

Rat Monoclonal Antibody

LMR-42 detects an outer-surface epitope of a 55 kDa plasma membrane protein overexpressed in several human non-Pgpmultidrug-resistant (MDR) tumor cell lines. Expression cloning revealed that the LMR-42 antigen is identical to the human endothelial cell protein Creceptor (EPCR). Protein C is the zymogen of the key anticoagulant enzyme, activated protein C (APC).

The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy.
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Specifications

Antigen EPCR
Applications Flow Cytometry, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone LMR-42
Concentration 100 μg/mL
Conjugate Unconjugated
Formulation Tissue culture supernatant with 0.7% BSA and 0.1% sodium azide
Gene Procr
Gene Accession No. Q9UNN8
Gene Alias Activated protein C receptor; AI325044; APC receptor; bA42O4.2; CCCA; CCD41; CD antigen CD201; CD201; CD201 antigen; cell cycle, centrosome-associated protein; centrocyclin; Centrosomal protein CCD41; endothelial cell protein C receptor; Endothelial protein C receptor; Epcr; PROCR; protein C receptor; protein C receptor, endothelial
Gene Symbols Procr
Host Species Rat
Immunogen Proprietary immunogen.
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10544
Target Species Human, Rat
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG2a
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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