Invitrogen™ Epha1 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA547435

Catalog No. PIPA547435

Description

In direct ELISAs, approximately 35% cross-reactivity with recombinant human EphA1 and less than 5% cross-reactivity with recombinant mouse (rm) EphA4, rmEphA6, and rmEphA7 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

EphA1 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EphA1 is expressed in some human cancer cell lines and has been implicated in carcinogenesis.

Specifications

• Antigen: Epha1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EPHA1
• Gene Alias: 5730453L17Rik; AL033318; Embryonic stem cell kinase; EPH; EPH receptor A1; EPH tyrosine kinase; EPH tyrosine kinase 1; EPHA1; ephrin receptor EphA1; ephrin type-A receptor 1; EPHT; EPHT1; erythropoietin-producing hepatoma amplified sequence; erythropoietin-producing hepatoma receptor; Esk; hEpha1; mEpha1; MGC163163; oncogene EPH; soluble EPHA1 variant 1; soluble EPHA1 variant 2; tyrosine-protein kinase receptor EPH; Tyrosine-protein kinase receptor ESK
• Host Species: Goat
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13835
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Flow Cytometry, Immunohistochemistry (Frozen), Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q60750
• Gene Symbols: EPHA1
• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse EphA1 Glu27-Glu548.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG